Deadly Fungal Meningitis Outbreak: What is it and what you can do

States where healthcare facilities received contaminated lots of steroids (C) CDC

This post was originally published at Mind the Science Gap on Oct. 25, 2012.

As of 4:30 PM on October 24th, 24 deaths have been reported due to a multi-state outbreak of fungal meningitis (swelling of the membranes of the brain or spine caused by a fungal infection). It is believed that the culprit is contaminated steroids, specifically methylprednisolone acetate, an injectable steroid to treat back and joint pain. While investigation of the causes of this outbreak is ongoing, specific lots of steroids made by the New England Compounding Company (NECC) have been pulled from use. NECC has since voluntarily ceased operations, recalled all products, and surrendered its pharmacy license.

What is Causing the Outbreak?

The primary causative organism is Exserohilum rostratum, a fungus typically found on plants and in the soil. It rarely causes disease in humans, and usually when it does infect humans it results in skin or sinus infections. This has made it difficult to provide precise information on when to expect symptoms to occur; the data are not available on fungal meningitis caused by E. rostratum. Continue reading